Data for: The use of FLIM for characterising chromosomes and their structure in response to low-dose X-ray irradiation

Abstract

The files in this repository are the raw and analysed data presented in the paper titled above. The experimental conditions are highlighted in the following published articles. We applied these methods to different DNA stains bound to chromosomes where only DAPI led to a clear lifetime difference between the chromosome arms (p,q). Our data showed that chromosomes of cells irradiated with 0.1 Gy and 1 Gy did not show a significant change in lifetimes. These findings indicate that DAPI FLT may be a useful tool to measure chromosomal structural changes and further suggests that chromosomes undergo distinct structural changes at the pericentromeric region following low-dose irradiation.